diff --git a/Cargo.lock b/Cargo.lock
index b00458a..ac43952 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -324,9 +324,9 @@ checksum = "95505c38b4572b2d910cecb0281560f54b440a19336cbbcb27bf6ce6adc6f5a8"
 
 [[package]]
 name = "hts-sys"
-version = "2.0.3"
+version = "2.1.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "0dba4fc406d3686926c84f98fd53026b625319d119e6056a40313862a6e3c4eb"
+checksum = "deebfb779c734d542e7f14c298597914b9b5425e4089aef482eacb5cab941915"
 dependencies = [
  "bzip2-sys",
  "cc",
@@ -619,9 +619,9 @@ checksum = "436b050e76ed2903236f032a59761c1eb99e1b0aead2c257922771dab1fc8c78"
 
 [[package]]
 name = "rust-htslib"
-version = "0.43.1"
+version = "0.44.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "53881800f22b91fa893cc3f6d70e6e9aa96d200133bfe112e36aee37aad70bf5"
+checksum = "7c7eb0f29fce64a4e22578905efef3d72389058016023279a58b282eb5c0c467"
 dependencies = [
  "bio-types",
  "byteorder",
diff --git a/Cargo.toml b/Cargo.toml
index 2e60fda..d34e68b 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -18,7 +18,7 @@ curl = ["rust-htslib/curl"]
 
 [dependencies]
 docopt = "*"
-rust-htslib = { version = "0.43", default-features = false }
+rust-htslib = { version = "0.44", default-features = false }
 flate2 = { version = "1.0", features = ["zlib"], default-features = false }
 libz-sys = "1.1.9"
 shardio = "0.8.2"