diff --git a/fuchsia/engine/browser/autoplay_browsertest.cc b/fuchsia/engine/browser/autoplay_browsertest.cc
index cb587a5c44cf9b..688a03052eaf79 100644
--- a/fuchsia/engine/browser/autoplay_browsertest.cc
+++ b/fuchsia/engine/browser/autoplay_browsertest.cc
@@ -49,9 +49,11 @@ class AutoplayTest : public cr_fuchsia::WebEngineBrowserTest {
   fuchsia::web::NavigationControllerPtr controller_;
 };
 
+// TODO(1162433): Flakily times-out, probably because URL will change as soon
+// as navigation is "committed", which happens before document load.
 IN_PROC_BROWSER_TEST_F(
     AutoplayTest,
-    UserActivationPolicy_UserActivatedViaSimulatedInteraction) {
+    DISABLED_UserActivationPolicy_UserActivatedViaSimulatedInteraction) {
   const GURL kUrl(embedded_test_server()->GetURL("/play_vp8.html?autoplay=1"));
 
   fuchsia::web::FramePtr frame =