diff --git a/tools/perf/record_wpr b/tools/perf/record_wpr
index 465163e9423906..dfe3d4db59f0d3 100755
--- a/tools/perf/record_wpr
+++ b/tools/perf/record_wpr
@@ -1,4 +1,4 @@
-#!/usr/bin/env python
+#!/usr/bin/env vpython
 # Copyright 2012 The Chromium Authors. All rights reserved.
 # Use of this source code is governed by a BSD-style license that can be
 # found in the LICENSE file.
diff --git a/tools/perf/run_benchmark b/tools/perf/run_benchmark
index 0a6e183cc5ab5d..91095101cbae1e 100755
--- a/tools/perf/run_benchmark
+++ b/tools/perf/run_benchmark
@@ -1,4 +1,4 @@
-#!/usr/bin/env python
+#!/usr/bin/env vpython
 # Copyright 2013 The Chromium Authors. All rights reserved.
 # Use of this source code is governed by a BSD-style license that can be
 # found in the LICENSE file.
diff --git a/tools/perf/run_telemetry_tests b/tools/perf/run_telemetry_tests
index 0abbd8a94b5c50..0d970e4f16f9db 100755
--- a/tools/perf/run_telemetry_tests
+++ b/tools/perf/run_telemetry_tests
@@ -1,4 +1,4 @@
-#!/usr/bin/env python
+#!/usr/bin/env vpython
 # Copyright 2016 The Chromium Authors. All rights reserved.
 # Use of this source code is governed by a BSD-style license that can be
 # found in the LICENSE file.
diff --git a/tools/perf/run_tests b/tools/perf/run_tests
index 152fa8575abd69..2ad55a05b14379 100755
--- a/tools/perf/run_tests
+++ b/tools/perf/run_tests
@@ -1,4 +1,4 @@
-#!/usr/bin/env python
+#!/usr/bin/env vpython
 # Copyright 2013 The Chromium Authors. All rights reserved.
 # Use of this source code is governed by a BSD-style license that can be
 # found in the LICENSE file.
diff --git a/tools/perf/scripts_smoke_unittest.py b/tools/perf/scripts_smoke_unittest.py
index 374ec22fb3a2c6..d99bc0b29e3f6e 100644
--- a/tools/perf/scripts_smoke_unittest.py
+++ b/tools/perf/scripts_smoke_unittest.py
@@ -16,11 +16,8 @@ class ScriptsSmokeTest(unittest.TestCase):
 
   perf_dir = os.path.dirname(__file__)
 
-  def RunPerfScript(self, command, venv=False):
+  def RunPerfScript(self, command):
     main_command = [sys.executable]
-    # TODO(crbug.com/805552): Remove if/else block
-    if venv:
-      main_command = ['vpython']
     args = main_command + command.split(' ')
     proc = subprocess.Popen(args, stdout=subprocess.PIPE,
                             stderr=subprocess.STDOUT, cwd=self.perf_dir)
@@ -50,8 +47,7 @@ def testRunRecordWprHelp(self):
 
   @decorators.Disabled('chromeos')  # crbug.com/814068
   def testRunRecordWprList(self):
-    return_code, stdout = self.RunPerfScript('record_wpr --list-benchmarks',
-        venv=True)
+    return_code, stdout = self.RunPerfScript('record_wpr --list-benchmarks')
     # TODO(nednguyen): Remove this once we figure out why importing
     # small_profile_extender fails on Android dbg.
     # crbug.com/561668