diff --git a/mesonbuild/backend/ninjabackend.py b/mesonbuild/backend/ninjabackend.py
index 17ac421ea3db..ba614fd564f7 100644
--- a/mesonbuild/backend/ninjabackend.py
+++ b/mesonbuild/backend/ninjabackend.py
@@ -1948,6 +1948,49 @@ def generate_rust_target(self, target: build.BuildTarget) -> None:
         args += output
         linkdirs = mesonlib.OrderedSet()
         external_deps = target.external_deps.copy()
+
+        # Have we already injected msvc-crt args?
+        #
+        # If we don't have A C, C++, or Fortran compiler that is
+        # VisualStudioLike treat this as if we've already injected them
+        #
+        # We handle this here rather than in the rust compiler because in
+        # general we don't want to link rust targets to a non-default crt.
+        # However, because of the way that MSCRTs work you can only link to one
+        # per target, so if A links to the debug one, and B links to the normal
+        # one you can't link A and B. Rust is hardcoded to the default one,
+        # so if we compile C/C++ code and link against a non-default MSCRT then
+        # linking will fail. We can work around this by injecting MSCRT link
+        # arguments early in the rustc command line
+        # https://github.com/rust-lang/rust/issues/39016
+        crt_args_injected = not any(x is not None and x.get_argument_syntax() == 'msvc' for x in
+                                    (self.environment.coredata.compilers[target.for_machine].get(l)
+                                     for l in ['c', 'cpp', 'fortran']))
+
+        crt_link_args: T.List[str] = []
+        try:
+            buildtype = self.environment.coredata.options[OptionKey('buildtype')].value
+            crt = self.environment.coredata.options[OptionKey('b_vscrt')].value
+            is_debug = buildtype == 'debug'
+
+            if crt == 'from_buildtype':
+                crt = 'mdd' if is_debug else 'md'
+            elif crt == 'static_from_buildtype':
+                crt = 'mtd' if is_debug else 'mt'
+
+            if crt == 'mdd':
+                crt_link_args = ['-l', 'static=msvcrtd']
+            elif crt == 'md':
+                # this is the default, no need to inject anything
+                crt_args_injected = True
+            elif crt == 'mtd':
+                crt_link_args = ['-l', 'static=libcmtd']
+            elif crt == 'mt':
+                crt_link_args = ['-l', 'static=libcmt']
+
+        except KeyError:
+            crt_args_injected = True
+
         # TODO: we likely need to use verbatim to handle name_prefix and name_suffix
         for d in target.link_targets:
             linkdirs.add(d.subdir)
@@ -1961,7 +2004,13 @@ def generate_rust_target(self, target: build.BuildTarget) -> None:
                 d_name = self._get_rust_dependency_name(target, d)
                 args += ['--extern', '{}={}'.format(d_name, os.path.join(d.subdir, d.filename))]
                 project_deps.append(RustDep(d_name, self.rust_crates[d.name].order))
-            elif isinstance(d, build.StaticLibrary):
+                continue
+
+            if not crt_args_injected and not {'c', 'cpp', 'fortran'}.isdisjoint(d.compilers):
+                args += crt_link_args
+                crt_args_injected = True
+
+            if isinstance(d, build.StaticLibrary):
                 # Rustc doesn't follow Meson's convention that static libraries
                 # are called .a, and import libraries are .lib, so we have to
                 # manually handle that.
@@ -2001,6 +2050,10 @@ def generate_rust_target(self, target: build.BuildTarget) -> None:
                 args += ['--extern', '{}={}'.format(d_name, os.path.join(d.subdir, d.filename))]
                 project_deps.append(RustDep(d_name, self.rust_crates[d.name].order))
             else:
+                if not crt_args_injected and not {'c', 'cpp', 'fortran'}.isdisjoint(d.compilers):
+                    crt_args_injected = True
+                    crt_args_injected = True
+
                 if rustc.linker.id in {'link', 'lld-link'}:
                     if verbatim:
                         # If we can use the verbatim modifier, then everything is great
diff --git a/test cases/rust/20 rust and cpp/test.json b/test cases/rust/20 rust and cpp/test.json
new file mode 100644
index 000000000000..c072a6c943de
--- /dev/null
+++ b/test cases/rust/20 rust and cpp/test.json	
@@ -0,0 +1,15 @@
+{
+  "matrix": {
+    "options": {
+      "b_vscrt": [
+        { "val": "none" },
+        { "val": "mdd" },
+        { "val": "md" },
+        { "val": "mtd" },
+        { "val": "mt" },
+        { "val": "from_buildtype" },
+        { "val": "static_from_buildtype" }
+      ]
+    }
+  }
+}