diff --git a/CHANGELOG.md b/CHANGELOG.md
index 773b8a7db7..9f42753dd3 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -13,6 +13,7 @@ For experimental package changes, see the [experimental CHANGELOG](experimental/
 
 * feat(instrumentation): generic config type in instrumentation base [#4659](https://github.com/open-telemetry/opentelemetry-js/pull/4659) @blumamir
 * feat: support node 22 [#4666](https://github.com/open-telemetry/opentelemetry-js/pull/4666) @dyladan
+* feat(sdk-trace-node): support `xray` Propagator via `OTEL_PROPAGATORS` environment variable [#4602](https://github.com/open-telemetry/opentelemetry-js/pull/4602) @anuraags
 
 ### :bug: (Bug Fix)
 
diff --git a/package-lock.json b/package-lock.json
index 24f328c018..fe4faeb55d 100644
--- a/package-lock.json
+++ b/package-lock.json
@@ -5960,6 +5960,7 @@
       }
     },
     "experimental/packages/propagator-aws-xray-lambda": {
+      "name": "@opentelemetry/propagator-aws-xray-lambda",
       "version": "0.51.0",
       "license": "Apache-2.0",
       "dependencies": {
@@ -36028,6 +36029,7 @@
       "dependencies": {
         "@opentelemetry/context-async-hooks": "1.24.0",
         "@opentelemetry/core": "1.24.0",
+        "@opentelemetry/propagator-aws-xray": "1.24.0",
         "@opentelemetry/propagator-b3": "1.24.0",
         "@opentelemetry/propagator-jaeger": "1.24.0",
         "@opentelemetry/sdk-trace-base": "1.24.0",
@@ -47039,6 +47041,7 @@
         "@opentelemetry/api": ">=1.0.0 <1.9.0",
         "@opentelemetry/context-async-hooks": "1.24.0",
         "@opentelemetry/core": "1.24.0",
+        "@opentelemetry/propagator-aws-xray": "1.24.0",
         "@opentelemetry/propagator-b3": "1.24.0",
         "@opentelemetry/propagator-jaeger": "1.24.0",
         "@opentelemetry/resources": "1.24.0",
diff --git a/packages/opentelemetry-sdk-trace-node/package.json b/packages/opentelemetry-sdk-trace-node/package.json
index 508eaa8bf9..f2b59159c7 100644
--- a/packages/opentelemetry-sdk-trace-node/package.json
+++ b/packages/opentelemetry-sdk-trace-node/package.json
@@ -68,6 +68,7 @@
     "@opentelemetry/context-async-hooks": "1.24.0",
     "@opentelemetry/core": "1.24.0",
     "@opentelemetry/propagator-b3": "1.24.0",
+    "@opentelemetry/propagator-aws-xray": "1.24.0",
     "@opentelemetry/propagator-jaeger": "1.24.0",
     "@opentelemetry/sdk-trace-base": "1.24.0",
     "semver": "^7.5.2"
diff --git a/packages/opentelemetry-sdk-trace-node/src/NodeTracerProvider.ts b/packages/opentelemetry-sdk-trace-node/src/NodeTracerProvider.ts
index 9d552162f6..c82b600d93 100644
--- a/packages/opentelemetry-sdk-trace-node/src/NodeTracerProvider.ts
+++ b/packages/opentelemetry-sdk-trace-node/src/NodeTracerProvider.ts
@@ -26,6 +26,7 @@ import {
 import * as semver from 'semver';
 import { NodeTracerConfig } from './config';
 import { JaegerPropagator } from '@opentelemetry/propagator-jaeger';
+import { AWSXRayPropagator } from '@opentelemetry/propagator-aws-xray';
 
 /**
  * Register this TracerProvider for use with the OpenTelemetry API.
@@ -50,6 +51,7 @@ export class NodeTracerProvider extends BasicTracerProvider {
       () => new B3Propagator({ injectEncoding: B3InjectEncoding.MULTI_HEADER }),
     ],
     ['jaeger', () => new JaegerPropagator()],
+    ['xray', () => new AWSXRayPropagator()],
   ]);
 
   constructor(config: NodeTracerConfig = {}) {
diff --git a/packages/opentelemetry-sdk-trace-node/test/NodeTracerProvider.test.ts b/packages/opentelemetry-sdk-trace-node/test/NodeTracerProvider.test.ts
index 1b1dbbd6d8..a0acf0d0d0 100644
--- a/packages/opentelemetry-sdk-trace-node/test/NodeTracerProvider.test.ts
+++ b/packages/opentelemetry-sdk-trace-node/test/NodeTracerProvider.test.ts
@@ -236,7 +236,7 @@ describe('NodeTracerProvider', () => {
     });
 
     it('should allow propagators as per the specification', () => {
-      (process.env as any).OTEL_PROPAGATORS = 'b3,b3multi,jaeger';
+      (process.env as any).OTEL_PROPAGATORS = 'b3,b3multi,jaeger,xray';
 
       const provider = new NodeTracerProvider();
       provider.register();
@@ -249,6 +249,7 @@ describe('NodeTracerProvider', () => {
         'x-b3-sampled',
         'x-b3-parentspanid',
         'uber-trace-id',
+        'x-amzn-trace-id',
       ]);
     });
   });
diff --git a/packages/opentelemetry-sdk-trace-node/tsconfig.json b/packages/opentelemetry-sdk-trace-node/tsconfig.json
index 31559ba9b3..a40ddeff36 100644
--- a/packages/opentelemetry-sdk-trace-node/tsconfig.json
+++ b/packages/opentelemetry-sdk-trace-node/tsconfig.json
@@ -32,6 +32,9 @@
     },
     {
       "path": "../opentelemetry-semantic-conventions"
+    },
+    {
+      "path": "../propagator-aws-xray"
     }
   ]
 }