diff --git a/components/brave_rewards/browser/publisher_info_database.cc b/components/brave_rewards/browser/publisher_info_database.cc
index 0110227310d8..ecee566af18a 100644
--- a/components/brave_rewards/browser/publisher_info_database.cc
+++ b/components/brave_rewards/browser/publisher_info_database.cc
@@ -645,6 +645,29 @@ bool PublisherInfoDatabase::GetActivityList(
   return true;
 }
 
+bool PublisherInfoDatabase::DeleteActivityInfo(
+    const std::string& publisher_key,
+    uint64_t reconcile_stamp) {
+  DCHECK_CALLED_ON_VALID_SEQUENCE(sequence_checker_);
+
+  bool initialized = Init();
+  DCHECK(initialized);
+
+  if (!initialized || publisher_key.empty() || reconcile_stamp == 0) {
+    return false;
+  }
+
+  sql::Statement statement(GetDB().GetCachedStatement(
+      SQL_FROM_HERE,
+      "DELETE FROM activity_info WHERE "
+      "publisher_id = ? AND reconcile_stamp = ?"));
+
+  statement.BindString(0, publisher_key);
+  statement.BindInt64(1, reconcile_stamp);
+
+  return statement.Run();
+}
+
 /**
  *
  * MEDIA PUBLISHER INFO
diff --git a/components/brave_rewards/browser/publisher_info_database.h b/components/brave_rewards/browser/publisher_info_database.h
index 6e451e1ae9a8..f311bf46a125 100644
--- a/components/brave_rewards/browser/publisher_info_database.h
+++ b/components/brave_rewards/browser/publisher_info_database.h
@@ -84,6 +84,9 @@ class PublisherInfoDatabase {
 
   void SetTestingCurrentVersion(int value);
 
+  bool DeleteActivityInfo(const std::string& publisher_key,
+                          uint64_t reconcile_stamp);
+
   // Vacuums the database. This will cause sqlite to defragment and collect
   // unused space in the file. It can be VERY SLOW.
   void Vacuum();
diff --git a/components/brave_rewards/browser/publisher_info_database_unittest.cc b/components/brave_rewards/browser/publisher_info_database_unittest.cc
index 66dfde35c23a..d9adbb707237 100644
--- a/components/brave_rewards/browser/publisher_info_database_unittest.cc
+++ b/components/brave_rewards/browser/publisher_info_database_unittest.cc
@@ -864,4 +864,55 @@ TEST_F(PublisherInfoDatabaseTest, GetExcludedPublishersCount) {
   EXPECT_EQ(publisher_info_database_->GetExcludedPublishersCount(), 2);
 }
 
+TEST_F(PublisherInfoDatabaseTest, DeleteActivityInfo) {
+  base::ScopedTempDir temp_dir;
+  base::FilePath db_file;
+  CreateTempDatabase(&temp_dir, &db_file);
+
+  ledger::PublisherInfo info;
+  info.id = "publisher_1";
+  info.verified = true;
+  info.excluded = ledger::PUBLISHER_EXCLUDE::DEFAULT;
+  info.name = "publisher1";
+  info.url = "https://publisher1.com";
+  info.duration = 10;
+  info.score = 1.1;
+  info.percent = 33;
+  info.weight = 1.5;
+  info.reconcile_stamp = 1;
+  info.visits = 1;
+
+  EXPECT_TRUE(publisher_info_database_->InsertOrUpdateActivityInfo(info));
+
+  info.reconcile_stamp = 2;
+  EXPECT_TRUE(publisher_info_database_->InsertOrUpdateActivityInfo(info));
+
+  info.id = "publisher_2";
+  info.name = "publisher2";
+  info.url = "https://publisher2.com";
+  EXPECT_TRUE(publisher_info_database_->InsertOrUpdateActivityInfo(info));
+
+  // publisher key is missing
+  EXPECT_FALSE(publisher_info_database_->DeleteActivityInfo("", 2));
+
+  // reconcile stamp is missing
+  EXPECT_FALSE(publisher_info_database_->DeleteActivityInfo("publisher_1", 0));
+
+  // publisher doesn't exist
+  EXPECT_TRUE(publisher_info_database_->DeleteActivityInfo("publisher_3", 2));
+
+  // publisher is deleted
+  EXPECT_TRUE(publisher_info_database_->DeleteActivityInfo("publisher_1", 2));
+  ledger::PublisherInfoList list;
+  ledger::ActivityInfoFilter filter;
+  filter.excluded = ledger::EXCLUDE_FILTER::FILTER_ALL;
+  EXPECT_TRUE(publisher_info_database_->GetActivityList(0, 0, filter, &list));
+  EXPECT_EQ(static_cast<int>(list.size()), 2);
+
+  EXPECT_EQ(list.at(0).id, "publisher_1");
+  EXPECT_EQ(list.at(0).reconcile_stamp, 1u);
+  EXPECT_EQ(list.at(1).id, "publisher_2");
+
+}
+
 }  // namespace brave_rewards
diff --git a/components/brave_rewards/browser/rewards_service_impl.cc b/components/brave_rewards/browser/rewards_service_impl.cc
index 61f7051cc8cd..d19f83526519 100644
--- a/components/brave_rewards/browser/rewards_service_impl.cc
+++ b/components/brave_rewards/browser/rewards_service_impl.cc
@@ -1903,8 +1903,14 @@ void RewardsServiceImpl::OnExcludedSitesChanged(
     ledger::PUBLISHER_EXCLUDE exclude) {
 
   bool excluded = exclude == ledger::PUBLISHER_EXCLUDE::EXCLUDED;
-  for (auto& observer : observers_)
+
+  if (excluded) {
+    DeleteActivityInfo(publisher_id);
+  }
+
+  for (auto& observer : observers_) {
     observer.OnExcludedSitesChanged(this, publisher_id, excluded);
+  }
 }
 
 void RewardsServiceImpl::OnPanelPublisherInfo(
@@ -2729,4 +2735,46 @@ void RewardsServiceImpl::GetExcludedPublishersNumberDB(
                      callback));
 }
 
+bool DeleteActivityInfoOnFileTaskRunner(PublisherInfoDatabase* backend,
+                                        const std::string& publisher_key,
+                                        uint64_t reconcile_stamp) {
+  if (backend &&
+      backend->DeleteActivityInfo(publisher_key, reconcile_stamp)) {
+    return true;
+  }
+
+  return false;
+}
+
+void RewardsServiceImpl::DeleteActivityInfo(const std::string& publisher_key) {
+  GetReconcileStamp(
+      base::Bind(&RewardsServiceImpl::OnDeleteActivityInfoStamp,
+                 AsWeakPtr(),
+                 publisher_key));
+}
+
+void RewardsServiceImpl::OnDeleteActivityInfoStamp(
+    const std::string& publisher_key,
+    uint64_t reconcile_stamp) {
+  base::PostTaskAndReplyWithResult(
+      file_task_runner_.get(),
+      FROM_HERE,
+      base::Bind(&DeleteActivityInfoOnFileTaskRunner,
+                 publisher_info_backend_.get(),
+                 publisher_key,
+                 reconcile_stamp),
+      base::Bind(&RewardsServiceImpl::OnDeleteActivityInfo,
+                 AsWeakPtr(),
+                 publisher_key));
+}
+
+void RewardsServiceImpl::OnDeleteActivityInfo(
+    const std::string& publisher_key,
+    bool result) {
+  if (!result) {
+    LOG(ERROR) << "Problem deleting activity info for "
+               << publisher_key;
+  }
+}
+
 }  // namespace brave_rewards
diff --git a/components/brave_rewards/browser/rewards_service_impl.h b/components/brave_rewards/browser/rewards_service_impl.h
index 0e71ad41cc42..a5652ecc5284 100644
--- a/components/brave_rewards/browser/rewards_service_impl.h
+++ b/components/brave_rewards/browser/rewards_service_impl.h
@@ -276,6 +276,14 @@ class RewardsServiceImpl : public RewardsService,
   void OnDonate(const std::string& publisher_key, int amount, bool recurring,
       std::unique_ptr<brave_rewards::ContentSite> site) override;
 
+  void DeleteActivityInfo(const std::string& publisher_key);
+
+  void OnDeleteActivityInfoStamp(const std::string& publisher_key,
+                                 uint64_t reconcile_stamp);
+
+  void OnDeleteActivityInfo(const std::string& publisher_key,
+                            bool result);
+
   // ledger::LedgerClient
   std::string GenerateGUID() const override;
   void OnWalletInitialized(ledger::Result result) override;