Exomiser 14.0.0 released! New Java version, new database format, smaller data downloads, more ACMG categories, better reporting...

[julesjacobsen]

• Minimum Java version is now Java 17
• Update database format REQUIRES DATABASE VERSION 2402 - these are significantly smaller than the previous versions (~50-60% of previous size) See the GitHub discussions section for details.
• Added new GeneBlacklistFilter #457
• Add new ClinVar conflicting evidence counts in HTML output #535
• Added PS1, PM1, PM5 categories to ACMG assignments
• Altered reporting of InheritanceModeFilter to state that the number shown refers to variants rather than genes.
• Updated gene constraints to use gnomad v4.0 data.
• TSV genes, TSV variants and VCF outputs will only write to a single file where the possible modes of inheritances are now shown together rather than split across separate files.
• Fix for issue #531 where the priorityScoreFilter and regulatoryFeatureFilter pass/fail counts were not displayed in the HTML.
• Fix for issue #534 where variant frequency and/or pathogenicity annotations are missing in certain run configurations.
• Fix for issue #541 where logging to /tmp/spring.log causes clashes in shared user environments.
• TSV output column CLINVAR_ALLELE_ID has been changed to CLINVAR_VARIANT_ID to allow easier reference to ClinVar variants.

Full Changelog: 13.3.0...14.0.0

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