diff --git a/packages/react-devtools-core/src/standalone.js b/packages/react-devtools-core/src/standalone.js
index 7eb246a28a316..e4e4ada1c31a9 100644
--- a/packages/react-devtools-core/src/standalone.js
+++ b/packages/react-devtools-core/src/standalone.js
@@ -279,7 +279,6 @@ function initialize(socket: WebSocket) {
   // $FlowFixMe[incompatible-call] found when upgrading Flow
   store = new Store(bridge, {
     checkBridgeProtocolCompatibility: true,
-    supportsNativeInspection: false,
     supportsTraceUpdates: true,
   });
 
diff --git a/packages/react-devtools-extensions/src/main/index.js b/packages/react-devtools-extensions/src/main/index.js
index 224e4cd4b4a8a..e1db3d505577b 100644
--- a/packages/react-devtools-extensions/src/main/index.js
+++ b/packages/react-devtools-extensions/src/main/index.js
@@ -97,6 +97,7 @@ function createBridgeAndStore() {
     // At this time, the timeline can only parse Chrome performance profiles.
     supportsTimeline: __IS_CHROME__,
     supportsTraceUpdates: true,
+    supportsNativeInspection: true,
   });
 
   if (!isProfiling) {
diff --git a/packages/react-devtools-fusebox/src/frontend.js b/packages/react-devtools-fusebox/src/frontend.js
index 68f5560bd9f98..976b8693d373e 100644
--- a/packages/react-devtools-fusebox/src/frontend.js
+++ b/packages/react-devtools-fusebox/src/frontend.js
@@ -37,7 +37,6 @@ export function createStore(bridge: FrontendBridge, config?: Config): Store {
   return new Store(bridge, {
     checkBridgeProtocolCompatibility: true,
     supportsTraceUpdates: true,
-    supportsNativeInspection: false,
     ...config,
   });
 }
diff --git a/packages/react-devtools-inline/src/frontend.js b/packages/react-devtools-inline/src/frontend.js
index 35897b9407e59..9031f6ffc7bd7 100644
--- a/packages/react-devtools-inline/src/frontend.js
+++ b/packages/react-devtools-inline/src/frontend.js
@@ -23,7 +23,6 @@ export function createStore(bridge: FrontendBridge, config?: Config): Store {
     checkBridgeProtocolCompatibility: true,
     supportsTraceUpdates: true,
     supportsTimeline: true,
-    supportsNativeInspection: false,
     ...config,
   });
 }
diff --git a/packages/react-devtools-shared/src/devtools/store.js b/packages/react-devtools-shared/src/devtools/store.js
index 3eb589b903dac..408151dcdbbaf 100644
--- a/packages/react-devtools-shared/src/devtools/store.js
+++ b/packages/react-devtools-shared/src/devtools/store.js
@@ -172,7 +172,7 @@ export default class Store extends EventEmitter<{
   _rootIDToRendererID: Map<number, number> = new Map();
 
   // These options may be initially set by a configuration option when constructing the Store.
-  _supportsNativeInspection: boolean = true;
+  _supportsNativeInspection: boolean = false;
   _supportsReloadAndProfile: boolean = false;
   _supportsTimeline: boolean = false;
   _supportsTraceUpdates: boolean = false;
@@ -216,7 +216,9 @@ export default class Store extends EventEmitter<{
         supportsTimeline,
         supportsTraceUpdates,
       } = config;
-      this._supportsNativeInspection = supportsNativeInspection !== false;
+      if (supportsNativeInspection) {
+        this._supportsNativeInspection = true;
+      }
       if (supportsReloadAndProfile) {
         this._supportsReloadAndProfile = true;
       }