diff --git a/CMakeLists.txt b/CMakeLists.txt
index a64bb28359..94c158c52c 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -65,8 +65,6 @@ set(CPACK_SOURCE_IGNORE_FILES
     /run_tests.py
     /integration_tests
     /compiler_tester
-    /setup.py    # remove from git
-    /MANIFEST.in # remove from git
 )
 include(CPack)
 # So that CPACK_PACKAGE_FILE_NAME prints the correct value below
diff --git a/MANIFEST.in b/MANIFEST.in
deleted file mode 100644
index cfc08d7dcb..0000000000
--- a/MANIFEST.in
+++ /dev/null
@@ -1,6 +0,0 @@
-recursive-include src *
-recursive-include cmake *
-include version
-include CMakeLists.txt
-include README.md
-include LICENSE
diff --git a/setup.py b/setup.py
deleted file mode 100644
index 4cad82ef4a..0000000000
--- a/setup.py
+++ /dev/null
@@ -1,53 +0,0 @@
-import os
-import setuptools
-import sys
-import skbuild
-
-with open("README.md", "r") as fh:
-    long_description = fh.read()
-
-with open("version", "r") as fh:
-    version = fh.read().strip()
-
-# scikit-build sometimes passes the incorrect MACOSX_DEPLOYMENT_TARGET value to
-# CMake. This ensures that the correct value is always passed in:
-cmake_args = []
-mdt = os.getenv("MACOSX_DEPLOYMENT_TARGET")
-if mdt:
-    cmake_args.append("-DCMAKE_OSX_DEPLOYMENT_TARGET={}".format(mdt))
-
-if sys.platform == "win32":
-    cmake_args.append("-DCMAKE_WINDOWS_EXPORT_ALL_SYMBOLS=TRUE")
-
-cmake_args.append("-DWITH_PYTHON=TRUE")
-
-skbuild.setup(
-    name="lfortran",
-    version=version,
-    author="Ondřej Čertík",
-    author_email="ondrej@certik.us",
-    description="Fortran compiler",
-    long_description=long_description,
-    long_description_content_type="text/markdown",
-    url="https://gitlab.com/lfortran/lfortran",
-    packages=setuptools.find_packages(),
-    include_package_data=True,
-    data_files=[
-        ('share/lfortran/nb', ['share/lfortran/nb/Demo.ipynb']),
-        ],
-    scripts=['lfort'],
-    cmake_args = cmake_args,
-    classifiers=[
-        "Programming Language :: Python :: 3",
-        "License :: OSI Approved :: MIT License",
-        "Operating System :: OS Independent",
-    ],
-    cmake_languages=('C'),
-    install_requires=[
-        "pytest",
-        "llvmlite",
-        "prompt_toolkit",
-        "antlr4-python3-runtime",
-        "pygments",
-    ],
-)