diff --git a/experimental/CHANGELOG.md b/experimental/CHANGELOG.md
index a8140469bf..d025c4d4b7 100644
--- a/experimental/CHANGELOG.md
+++ b/experimental/CHANGELOG.md
@@ -19,6 +19,7 @@ All notable changes to experimental packages in this project will be documented
 ### :bug: (Bug Fix)
 
 * fix(prometheus-exporter): add possibility to respond to errors returned by `server.listen()` [#3552](https://github.com/open-telemetry/opentelemetry-js/pull/3402) @pichlermarc
+  fix(sdk-node): update instrumentations once MeterProvider is initialized [#3624](https://github.com/open-telemetry/opentelemetry-js/pull/3624) @pichlermarc
 
 ### :books: (Refine Doc)
 
diff --git a/experimental/packages/opentelemetry-sdk-node/src/sdk.ts b/experimental/packages/opentelemetry-sdk-node/src/sdk.ts
index 8b0e539eeb..dc9244f3e4 100644
--- a/experimental/packages/opentelemetry-sdk-node/src/sdk.ts
+++ b/experimental/packages/opentelemetry-sdk-node/src/sdk.ts
@@ -48,6 +48,7 @@ import { SemanticResourceAttributes } from '@opentelemetry/semantic-conventions'
 import { NodeSDKConfiguration } from './types';
 import { TracerProviderWithEnvExporters } from './TracerProviderWithEnvExporter';
 import { getEnv } from '@opentelemetry/core';
+import { parseInstrumentationOptions } from './utils';
 
 /** This class represents everything needed to register a fully configured OpenTelemetry Node.js SDK */
 
@@ -61,6 +62,7 @@ export type MeterProviderConfig = {
    */
   views?: View[];
 };
+
 export class NodeSDK {
   private _tracerProviderConfig?: {
     tracerConfig: NodeTracerConfig;
@@ -275,6 +277,15 @@ export class NodeSDK {
       this._meterProvider = meterProvider;
 
       metrics.setGlobalMeterProvider(meterProvider);
+
+      // TODO: This is a workaround to fix https://github.com/open-telemetry/opentelemetry-js/issues/3609
+      // If the MeterProvider is not yet registered when instrumentations are registered, all metrics are dropped.
+      // This code is obsolete once https://github.com/open-telemetry/opentelemetry-js/issues/3622 is implemented.
+      for (const instrumentation of parseInstrumentationOptions(
+        this._instrumentations
+      )) {
+        instrumentation.setMeterProvider(metrics.getMeterProvider());
+      }
     }
   }
 
diff --git a/experimental/packages/opentelemetry-sdk-node/src/utils.ts b/experimental/packages/opentelemetry-sdk-node/src/utils.ts
new file mode 100644
index 0000000000..a3d8314747
--- /dev/null
+++ b/experimental/packages/opentelemetry-sdk-node/src/utils.ts
@@ -0,0 +1,43 @@
+/*
+ * Copyright The OpenTelemetry Authors
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      https://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+
+import {
+  Instrumentation,
+  InstrumentationOption,
+} from '@opentelemetry/instrumentation';
+
+// TODO: This part of a workaround to fix https://github.com/open-telemetry/opentelemetry-js/issues/3609
+// If the MeterProvider is not yet registered when instrumentations are registered, all metrics are dropped.
+// This code is obsolete once https://github.com/open-telemetry/opentelemetry-js/issues/3622 is implemented.
+export function parseInstrumentationOptions(
+  options: InstrumentationOption[] = []
+): Instrumentation[] {
+  let instrumentations: Instrumentation[] = [];
+  for (let i = 0, j = options.length; i < j; i++) {
+    // eslint-disable-next-line @typescript-eslint/no-explicit-any
+    const option = options[i] as any;
+    if (Array.isArray(option)) {
+      const results = parseInstrumentationOptions(option);
+      instrumentations = instrumentations.concat(results);
+    } else if (typeof option === 'function') {
+      instrumentations.push(new option());
+    } else if ((option as Instrumentation).instrumentationName) {
+      instrumentations.push(option);
+    }
+  }
+
+  return instrumentations;
+}