diff --git a/compiler/rustc_codegen_llvm/src/back/write.rs b/compiler/rustc_codegen_llvm/src/back/write.rs
index 9d5204034def0..ef9ae2afca22d 100644
--- a/compiler/rustc_codegen_llvm/src/back/write.rs
+++ b/compiler/rustc_codegen_llvm/src/back/write.rs
@@ -571,7 +571,6 @@ pub(crate) unsafe fn llvm_optimize(
         unroll_loops,
         config.vectorize_slp,
         config.vectorize_loop,
-        config.no_builtins,
         config.emit_lifetime_markers,
         sanitizer_options.as_ref(),
         pgo_gen_path.as_ref().map_or(std::ptr::null(), |s| s.as_ptr()),
@@ -686,7 +685,6 @@ pub(crate) unsafe fn codegen(
         unsafe fn with_codegen<'ll, F, R>(
             tm: &'ll llvm::TargetMachine,
             llmod: &'ll llvm::Module,
-            no_builtins: bool,
             f: F,
         ) -> R
         where
@@ -694,7 +692,7 @@ pub(crate) unsafe fn codegen(
         {
             let cpm = llvm::LLVMCreatePassManager();
             llvm::LLVMAddAnalysisPasses(tm, cpm);
-            llvm::LLVMRustAddLibraryInfo(cpm, llmod, no_builtins);
+            llvm::LLVMRustAddLibraryInfo(cpm, llmod);
             f(cpm)
         }
 
@@ -797,7 +795,7 @@ pub(crate) unsafe fn codegen(
             } else {
                 llmod
             };
-            with_codegen(tm, llmod, config.no_builtins, |cpm| {
+            with_codegen(tm, llmod, |cpm| {
                 write_output_file(
                     diag_handler,
                     tm,
@@ -832,7 +830,7 @@ pub(crate) unsafe fn codegen(
                     (_, SplitDwarfKind::Split) => Some(dwo_out.as_path()),
                 };
 
-                with_codegen(tm, llmod, config.no_builtins, |cpm| {
+                with_codegen(tm, llmod, |cpm| {
                     write_output_file(
                         diag_handler,
                         tm,
diff --git a/compiler/rustc_codegen_llvm/src/llvm/ffi.rs b/compiler/rustc_codegen_llvm/src/llvm/ffi.rs
index a038b3af03dd6..528447b016aa3 100644
--- a/compiler/rustc_codegen_llvm/src/llvm/ffi.rs
+++ b/compiler/rustc_codegen_llvm/src/llvm/ffi.rs
@@ -2139,13 +2139,8 @@ extern "C" {
         ArgsCstrBuff: *const c_char,
         ArgsCstrBuffLen: usize,
     ) -> *mut TargetMachine;
-
     pub fn LLVMRustDisposeTargetMachine(T: *mut TargetMachine);
-    pub fn LLVMRustAddLibraryInfo<'a>(
-        PM: &PassManager<'a>,
-        M: &'a Module,
-        DisableSimplifyLibCalls: bool,
-    );
+    pub fn LLVMRustAddLibraryInfo<'a>(PM: &PassManager<'a>, M: &'a Module);
     pub fn LLVMRustWriteOutputFile<'a>(
         T: &'a TargetMachine,
         PM: &PassManager<'a>,
@@ -2167,7 +2162,6 @@ extern "C" {
         UnrollLoops: bool,
         SLPVectorize: bool,
         LoopVectorize: bool,
-        DisableSimplifyLibCalls: bool,
         EmitLifetimeMarkers: bool,
         SanitizerOptions: Option<&SanitizerOptions>,
         PGOGenPath: *const c_char,
diff --git a/compiler/rustc_codegen_ssa/src/back/link.rs b/compiler/rustc_codegen_ssa/src/back/link.rs
index c0f6e7cb7b0b3..0f45bcb7e978c 100644
--- a/compiler/rustc_codegen_ssa/src/back/link.rs
+++ b/compiler/rustc_codegen_ssa/src/back/link.rs
@@ -518,8 +518,7 @@ fn link_staticlib<'a>(
         &codegen_results.crate_info,
         Some(CrateType::Staticlib),
         &mut |cnum, path| {
-            let lto = are_upstream_rust_objects_already_included(sess)
-                && !ignored_for_lto(sess, &codegen_results.crate_info, cnum);
+            let lto = are_upstream_rust_objects_already_included(sess);
 
             let native_libs = codegen_results.crate_info.native_libraries[&cnum].iter();
             let relevant = native_libs.clone().filter(|lib| relevant_lib(sess, &lib));
@@ -1258,24 +1257,6 @@ fn link_sanitizer_runtime(sess: &Session, linker: &mut dyn Linker, name: &str) {
     }
 }
 
-/// Returns a boolean indicating whether the specified crate should be ignored
-/// during LTO.
-///
-/// Crates ignored during LTO are not lumped together in the "massive object
-/// file" that we create and are linked in their normal rlib states. See
-/// comments below for what crates do not participate in LTO.
-///
-/// It's unusual for a crate to not participate in LTO. Typically only
-/// compiler-specific and unstable crates have a reason to not participate in
-/// LTO.
-pub fn ignored_for_lto(sess: &Session, info: &CrateInfo, cnum: CrateNum) -> bool {
-    // If our target enables builtin function lowering in LLVM then the
-    // crates providing these functions don't participate in LTO (e.g.
-    // no_builtins or compiler builtins crates).
-    !sess.target.no_builtins
-        && (info.compiler_builtins == Some(cnum) || info.is_no_builtins.contains(&cnum))
-}
-
 /// This functions tries to determine the appropriate linker (and corresponding LinkerFlavor) to use
 pub fn linker_and_flavor(sess: &Session) -> (PathBuf, LinkerFlavor) {
     fn infer_from(
@@ -2718,10 +2699,6 @@ fn rehome_sysroot_lib_dir<'a>(sess: &'a Session, lib_dir: &Path) -> PathBuf {
 // symbols). We must continue to include the rest of the rlib, however, as
 // it may contain static native libraries which must be linked in.
 //
-// (*) Crates marked with `#![no_builtins]` don't participate in LTO and
-// their bytecode wasn't included. The object files in those libraries must
-// still be passed to the linker.
-//
 // Note, however, that if we're not doing LTO we can just pass the rlib
 // blindly to the linker (fast) because it's fine if it's not actually
 // included as we're at the end of the dependency chain.
@@ -2747,9 +2724,7 @@ fn add_static_crate<'a>(
         cmd.link_rlib(&rlib_path);
     };
 
-    if !are_upstream_rust_objects_already_included(sess)
-        || ignored_for_lto(sess, &codegen_results.crate_info, cnum)
-    {
+    if !are_upstream_rust_objects_already_included(sess) {
         link_upstream(cratepath);
         return;
     }
@@ -2763,8 +2738,6 @@ fn add_static_crate<'a>(
         let canonical_name = name.replace('-', "_");
         let upstream_rust_objects_already_included =
             are_upstream_rust_objects_already_included(sess);
-        let is_builtins =
-            sess.target.no_builtins || !codegen_results.crate_info.is_no_builtins.contains(&cnum);
 
         let mut archive = archive_builder_builder.new_archive_builder(sess);
         if let Err(error) = archive.add_archive(
@@ -2781,9 +2754,8 @@ fn add_static_crate<'a>(
 
                 // If we're performing LTO and this is a rust-generated object
                 // file, then we don't need the object file as it's part of the
-                // LTO module. Note that `#![no_builtins]` is excluded from LTO,
-                // though, so we let that object file slide.
-                if upstream_rust_objects_already_included && is_rust_object && is_builtins {
+                // LTO module.
+                if upstream_rust_objects_already_included && is_rust_object {
                     return true;
                 }
 
diff --git a/compiler/rustc_codegen_ssa/src/back/symbol_export.rs b/compiler/rustc_codegen_ssa/src/back/symbol_export.rs
index 9cd4394108a4a..0e436f247b0b6 100644
--- a/compiler/rustc_codegen_ssa/src/back/symbol_export.rs
+++ b/compiler/rustc_codegen_ssa/src/back/symbol_export.rs
@@ -54,8 +54,8 @@ fn reachable_non_generics_provider(tcx: TyCtxt<'_>, _: LocalCrate) -> DefIdMap<S
     // export level, however, as they're just implementation details.
     // Down below we'll hardwire all of the symbols to the `Rust` export
     // level instead.
-    let special_runtime_crate =
-        tcx.is_panic_runtime(LOCAL_CRATE) || tcx.is_compiler_builtins(LOCAL_CRATE);
+    let is_compiler_builtins = tcx.is_compiler_builtins(LOCAL_CRATE);
+    let special_runtime_crate = tcx.is_panic_runtime(LOCAL_CRATE) || is_compiler_builtins;
 
     let mut reachable_non_generics: DefIdMap<_> = tcx
         .reachable_set(())
@@ -107,7 +107,11 @@ fn reachable_non_generics_provider(tcx: TyCtxt<'_>, _: LocalCrate) -> DefIdMap<S
         .map(|def_id| {
             // We won't link right if this symbol is stripped during LTO.
             let name = tcx.symbol_name(Instance::mono(tcx, def_id.to_def_id())).name;
-            let used = name == "rust_eh_personality";
+            // We have to preserve the symbols of the built-in functions during LTO.
+            let is_builtin_fn = is_compiler_builtins
+                && symbol_export_level(tcx, def_id.to_def_id())
+                    .is_below_threshold(SymbolExportLevel::C);
+            let used = is_builtin_fn || name == "rust_eh_personality";
 
             let export_level = if special_runtime_crate {
                 SymbolExportLevel::Rust
diff --git a/compiler/rustc_codegen_ssa/src/back/write.rs b/compiler/rustc_codegen_ssa/src/back/write.rs
index 3d6a212433463..587b0cc33f456 100644
--- a/compiler/rustc_codegen_ssa/src/back/write.rs
+++ b/compiler/rustc_codegen_ssa/src/back/write.rs
@@ -148,23 +148,12 @@ impl ModuleConfig {
 
         let emit_obj = if !should_emit_obj {
             EmitObj::None
-        } else if sess.target.obj_is_bitcode
-            || (sess.opts.cg.linker_plugin_lto.enabled() && !no_builtins)
-        {
+        } else if sess.target.obj_is_bitcode || sess.opts.cg.linker_plugin_lto.enabled() {
             // This case is selected if the target uses objects as bitcode, or
             // if linker plugin LTO is enabled. In the linker plugin LTO case
             // the assumption is that the final link-step will read the bitcode
             // and convert it to object code. This may be done by either the
             // native linker or rustc itself.
-            //
-            // Note, however, that the linker-plugin-lto requested here is
-            // explicitly ignored for `#![no_builtins]` crates. These crates are
-            // specifically ignored by rustc's LTO passes and wouldn't work if
-            // loaded into the linker. These crates define symbols that LLVM
-            // lowers intrinsics to, and these symbol dependencies aren't known
-            // until after codegen. As a result any crate marked
-            // `#![no_builtins]` is assumed to not participate in LTO and
-            // instead goes on to generate object code.
             EmitObj::Bitcode
         } else if need_bitcode_in_object(tcx) {
             EmitObj::ObjectCode(BitcodeSection::Full)
@@ -1037,9 +1026,6 @@ fn start_executing_work<B: ExtraBackendMethods>(
 
     let mut each_linked_rlib_for_lto = Vec::new();
     drop(link::each_linked_rlib(crate_info, None, &mut |cnum, path| {
-        if link::ignored_for_lto(sess, crate_info, cnum) {
-            return;
-        }
         each_linked_rlib_for_lto.push((cnum, path.to_path_buf()));
     }));
 
diff --git a/compiler/rustc_codegen_ssa/src/base.rs b/compiler/rustc_codegen_ssa/src/base.rs
index 198e5696357af..f7223de79652d 100644
--- a/compiler/rustc_codegen_ssa/src/base.rs
+++ b/compiler/rustc_codegen_ssa/src/base.rs
@@ -854,7 +854,6 @@ impl CrateInfo {
             local_crate_name,
             compiler_builtins,
             profiler_runtime: None,
-            is_no_builtins: Default::default(),
             native_libraries: Default::default(),
             used_libraries: tcx.native_libraries(LOCAL_CRATE).iter().map(Into::into).collect(),
             crate_name: Default::default(),
@@ -881,9 +880,6 @@ impl CrateInfo {
             if tcx.is_profiler_runtime(cnum) {
                 info.profiler_runtime = Some(cnum);
             }
-            if tcx.is_no_builtins(cnum) {
-                info.is_no_builtins.insert(cnum);
-            }
         }
 
         // Handle circular dependencies in the standard library.
@@ -891,9 +887,7 @@ impl CrateInfo {
         // If global LTO is enabled then almost everything (*) is glued into a single object file,
         // so this logic is not necessary and can cause issues on some targets (due to weak lang
         // item symbols being "privatized" to that object file), so we disable it.
-        // (*) Native libs, and `#[compiler_builtins]` and `#[no_builtins]` crates are not glued,
-        // and we assume that they cannot define weak lang items. This is not currently enforced
-        // by the compiler, but that's ok because all this stuff is unstable anyway.
+        // (*) Native libs are not glued, and we assume that they cannot define weak lang items.
         let target = &tcx.sess.target;
         if !are_upstream_rust_objects_already_included(tcx.sess) {
             let missing_weak_lang_items: FxHashSet<Symbol> = info
diff --git a/compiler/rustc_codegen_ssa/src/lib.rs b/compiler/rustc_codegen_ssa/src/lib.rs
index 156c2904f4075..a4a621941c41f 100644
--- a/compiler/rustc_codegen_ssa/src/lib.rs
+++ b/compiler/rustc_codegen_ssa/src/lib.rs
@@ -25,7 +25,7 @@ extern crate tracing;
 extern crate rustc_middle;
 
 use rustc_ast as ast;
-use rustc_data_structures::fx::{FxHashMap, FxHashSet};
+use rustc_data_structures::fx::FxHashMap;
 use rustc_data_structures::sync::Lrc;
 use rustc_errors::{DiagnosticMessage, SubdiagnosticMessage};
 use rustc_fluent_macro::fluent_messages;
@@ -159,7 +159,6 @@ pub struct CrateInfo {
     pub local_crate_name: Symbol,
     pub compiler_builtins: Option<CrateNum>,
     pub profiler_runtime: Option<CrateNum>,
-    pub is_no_builtins: FxHashSet<CrateNum>,
     pub native_libraries: FxHashMap<CrateNum, Vec<NativeLib>>,
     pub crate_name: FxHashMap<CrateNum, Symbol>,
     pub used_libraries: Vec<NativeLib>,
diff --git a/compiler/rustc_llvm/llvm-wrapper/PassWrapper.cpp b/compiler/rustc_llvm/llvm-wrapper/PassWrapper.cpp
index 31565db1b7929..ff2ec388a5f2c 100644
--- a/compiler/rustc_llvm/llvm-wrapper/PassWrapper.cpp
+++ b/compiler/rustc_llvm/llvm-wrapper/PassWrapper.cpp
@@ -535,12 +535,9 @@ extern "C" void LLVMRustDisposeTargetMachine(LLVMTargetMachineRef TM) {
 
 // Unfortunately, the LLVM C API doesn't provide a way to create the
 // TargetLibraryInfo pass, so we use this method to do so.
-extern "C" void LLVMRustAddLibraryInfo(LLVMPassManagerRef PMR, LLVMModuleRef M,
-                                       bool DisableSimplifyLibCalls) {
+extern "C" void LLVMRustAddLibraryInfo(LLVMPassManagerRef PMR, LLVMModuleRef M) {
   Triple TargetTriple(unwrap(M)->getTargetTriple());
   TargetLibraryInfoImpl TLII(TargetTriple);
-  if (DisableSimplifyLibCalls)
-    TLII.disableAllFunctions();
   unwrap(PMR)->add(new TargetLibraryInfoWrapperPass(TLII));
 }
 
@@ -707,7 +704,7 @@ LLVMRustOptimize(
     bool IsLinkerPluginLTO,
     bool NoPrepopulatePasses, bool VerifyIR, bool UseThinLTOBuffers,
     bool MergeFunctions, bool UnrollLoops, bool SLPVectorize, bool LoopVectorize,
-    bool DisableSimplifyLibCalls, bool EmitLifetimeMarkers,
+    bool EmitLifetimeMarkers,
     LLVMRustSanitizerOptions *SanitizerOptions,
     const char *PGOGenPath, const char *PGOUsePath,
     bool InstrumentCoverage, const char *InstrProfileOutput,
@@ -813,8 +810,6 @@ LLVMRustOptimize(
 
   Triple TargetTriple(TheModule->getTargetTriple());
   std::unique_ptr<TargetLibraryInfoImpl> TLII(new TargetLibraryInfoImpl(TargetTriple));
-  if (DisableSimplifyLibCalls)
-    TLII->disableAllFunctions();
   FAM.registerPass([&] { return TargetLibraryAnalysis(*TLII); });
 
   PB.registerModuleAnalyses(MAM);
diff --git a/tests/run-make/no-builtins-lto/Makefile b/tests/run-make/no-builtins-lto/Makefile
index c8f05d9918b91..717d047c4469d 100644
--- a/tests/run-make/no-builtins-lto/Makefile
+++ b/tests/run-make/no-builtins-lto/Makefile
@@ -1,9 +1,15 @@
 include ../tools.mk
 
+# only-x86_64
+
+# We want to check that `no_builtins` is correctly participating in LTO.
+# First, verify that the `foo::foo` symbol can be found when linking.
+# Next, verify that `memcpy` can be customized using `no_builtins` under LTO.
+# Others will use the built-in memcpy.
+
 all:
-	# Compile a `#![no_builtins]` rlib crate
-	$(RUSTC) no_builtins.rs
-	# Build an executable that depends on that crate using LTO. The no_builtins crate doesn't
-	# participate in LTO, so its rlib must be explicitly linked into the final binary. Verify this by
-	# grepping the linker arguments.
-	$(RUSTC) main.rs -C lto --print link-args | $(CGREP) 'libno_builtins.rlib'
+	$(RUSTC) -C linker-plugin-lto -C opt-level=2 -C debuginfo=0 foo.rs
+	$(RUSTC) -C linker-plugin-lto -C opt-level=2 -C debuginfo=0 no_builtins.rs
+	$(RUSTC) main.rs -C lto -C opt-level=2 -C debuginfo=0 -C save-temps -C metadata=1 -C codegen-units=1
+	$(LLVM_BIN_DIR)/llvm-dis $(TMPDIR)/main.main.*-cgu.0.rcgu.lto.input.bc -o $(TMPDIR)/lto.ll
+	cat "$(TMPDIR)"/lto.ll | "$(LLVM_FILECHECK)" filecheck.lto.txt
diff --git a/tests/run-make/no-builtins-lto/filecheck.lto.txt b/tests/run-make/no-builtins-lto/filecheck.lto.txt
new file mode 100644
index 0000000000000..79dc3a51501db
--- /dev/null
+++ b/tests/run-make/no-builtins-lto/filecheck.lto.txt
@@ -0,0 +1,17 @@
+CHECK: define{{.*}} void @bar
+CHECK-NEXT: call void @no_builtins
+CHECK-NEXT: call void @llvm.memcpy
+
+CHECK: define{{.*}} i32 @main
+CHECK: call void @bar
+
+CHECK: define{{.*}} void @foo
+CHECK-NEXT: call void @llvm.memcpy
+
+CHECK: define{{.*}} void @no_builtins
+CHECK-SAME: #[[ATTR:[0-9]+]] {
+CHECK: call void @foo
+CHECK-NEXT: call{{.*}} @memcpy
+
+CHECK: attributes #[[ATTR]]
+CHECK-SAME: no-builtins
diff --git a/tests/run-make/no-builtins-lto/foo.rs b/tests/run-make/no-builtins-lto/foo.rs
new file mode 100644
index 0000000000000..f09ac40b152a2
--- /dev/null
+++ b/tests/run-make/no-builtins-lto/foo.rs
@@ -0,0 +1,33 @@
+#![feature(lang_items, no_core)]
+#![no_std]
+#![no_core]
+#![crate_type = "lib"]
+
+#[inline(never)]
+#[no_mangle]
+pub unsafe fn foo(dest: *mut u8, src: *const u8) {
+    // should call `@llvm.memcpy`.
+    memcpy(dest, src, 1024);
+}
+
+#[no_mangle]
+#[inline(never)]
+pub unsafe extern "C" fn memcpy(dest: *mut u8, src: *const u8, _n: usize) -> *mut u8 {
+    *dest = 0;
+    return src as *mut u8;
+}
+
+#[lang = "sized"]
+trait Sized {}
+#[lang = "copy"]
+trait Copy {}
+impl Copy for *mut u8 {}
+impl Copy for *const u8 {}
+
+#[lang = "drop_in_place"]
+#[allow(unconditional_recursion)]
+pub unsafe fn drop_in_place<T: ?Sized>(to_drop: *mut T) {
+    // Code here does not matter - this is replaced by the
+    // real drop glue by the compiler.
+    drop_in_place(to_drop);
+}
diff --git a/tests/run-make/no-builtins-lto/main.rs b/tests/run-make/no-builtins-lto/main.rs
index 890c999c8ccf7..c474527a5ae80 100644
--- a/tests/run-make/no-builtins-lto/main.rs
+++ b/tests/run-make/no-builtins-lto/main.rs
@@ -1,3 +1,28 @@
+#![feature(no_core, start, lang_items)]
+#![no_std]
+// We use `no_core` to reduce the LTO products is small enough.
+#![no_core]
+
 extern crate no_builtins;
+extern crate foo;
+
+#[link(name = "c")]
+extern "C" {}
+
+#[start]
+fn main(_: isize, p: *const *const u8) -> isize {
+    // Make sure the symbols are retained.
+    unsafe { bar(*p as *mut u8, *p); }
+    0
+}
+
+#[no_mangle]
+#[inline(never)]
+pub unsafe extern "C" fn bar(dest: *mut u8, src: *const u8) {
+    no_builtins::no_builtins(dest, src);
+    // should call `@llvm.memcpy`
+    foo::memcpy(dest, src, 1024);
+}
 
-fn main() {}
+#[lang = "eh_personality"]
+fn eh_personality() {}
diff --git a/tests/run-make/no-builtins-lto/no_builtins.rs b/tests/run-make/no-builtins-lto/no_builtins.rs
index 5d001031a57fa..33ed68e3aee3d 100644
--- a/tests/run-make/no-builtins-lto/no_builtins.rs
+++ b/tests/run-make/no-builtins-lto/no_builtins.rs
@@ -1,2 +1,15 @@
+#![feature(lang_items, no_core)]
+#![no_std]
+#![no_core]
 #![crate_type = "lib"]
 #![no_builtins]
+
+extern crate foo;
+
+#[no_mangle]
+pub unsafe fn no_builtins(dest: *mut u8, src: *const u8) {
+    // There should be no "undefined reference to `foo::foo'".
+    foo::foo(dest, src);
+    // should call `@memcpy` instead of `@llvm.memcpy`.
+    foo::memcpy(dest, src, 1024);
+}
diff --git a/tests/run-make/wasm-spurious-import/Makefile b/tests/run-make/wasm-builtins-import/Makefile
similarity index 100%
rename from tests/run-make/wasm-spurious-import/Makefile
rename to tests/run-make/wasm-builtins-import/Makefile
diff --git a/tests/run-make/wasm-spurious-import/main.rs b/tests/run-make/wasm-builtins-import/main.rs
similarity index 61%
rename from tests/run-make/wasm-spurious-import/main.rs
rename to tests/run-make/wasm-builtins-import/main.rs
index fcbead5e28bd2..5eb99df6ff74c 100644
--- a/tests/run-make/wasm-spurious-import/main.rs
+++ b/tests/run-make/wasm-builtins-import/main.rs
@@ -8,7 +8,8 @@ fn my_panic(_info: &core::panic::PanicInfo) -> ! {
 
 #[no_mangle]
 pub fn multer(a: i128, b: i128) -> i128 {
-    // Trigger usage of the __multi3 compiler intrinsic which then leads to an imported
-    // panic function in case of a bug. We verify that no imports exist in our verifier.
+    // Trigger usage of the __multi3 compiler intrinsic which then leads to an imported function
+    // such as panic or __multi3 (externally defined) in case of a bug. We verify that
+    // no imports exist in our verifier.
     a * b
 }
diff --git a/tests/run-make/wasm-spurious-import/verify.js b/tests/run-make/wasm-builtins-import/verify.js
similarity index 100%
rename from tests/run-make/wasm-spurious-import/verify.js
rename to tests/run-make/wasm-builtins-import/verify.js