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RNA Pol II Length and Disorder Enable Cooperative Scaling of Transcriptional Bursting

DOI

This repository contains all the code used for data analysis in this paper by Porfirio Quintero-Cadena, Tineke L. Lenstra and Paul W. Sternberg.

Requires python 3.6

analysis

Generate data that can be visualized: extract features from imaging, sequencing and simulation data.

figures

Generate all main and supplementary figures. Almost every figure* can be generated and saved in figures/output by running python figures/figureX.py from this directory, where X is the figure script suffix.

*Except for figures that require a file larger than github's 100MB size limit (Figures 6F, S2 and S8). Those figures will be skipped automatically if the file is not found.

utils

Supporting functions for data analysis.

data

Output from analysis functions used to generate figures. Mostly csv files

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