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PK-Sim® is a comprehensive software tool for whole-body physiologically based pharmacokinetic modeling
Physiologically Based Pharmacokinetic Models for Pregnant Women
Whole-body PBPK model of digoxin as P-gp DDI victim drug
Whole-body PBPK model of Vancomycin
Updated
Oct 14, 2021
MATLAB
Whole-body PBPK model of theophylline as CYP1A2 DDI victim drug
Modeling of published clinical Clarithromycin-Midazolam-DDI studies for model evaluation
Whole-body PBPK model of levonorgestrel with and without ethinyl estradiol as CYP3A4 DDI victim drug
Whole-body PBPK model of voriconazole as CYP2C19 substrate and CYP3A4 perpetrator drug
PBPK model of metoprolol and metoprolol-CYP2D6 drug-gene interactions
PK-Sim® & MoBi® workshop on integrating PBPK with QSP
Modeling of published clinical Itraconazole-Digoxin-DDI studies for model evaluation
Whole-body PBPK model of gemfibrozil as CYP2C8 and OATP1B1 DDI perpetrator drug
Whole-body PBPK model of Irinotecan (CPT-11) & SN-38 determining tumor tissue kinetics of both parent drug & active metabolite.
Whole-body PBPK model of probenecid (OAT perpetrator drug)
Whole-body PBPK model of finerenone (KERENDIA).
Modeling of published clinical gemfibrozil-pioglitazone-DDI studies for model evaluation
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