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ISOP QSP Webinar Series: Bridging and Tackling the Gap between Empirical and Systems Pharmacology Models: Where do we stand? Part 7: PK-Sim/Mobi – Open Systems Pharmacology Suite by Jan Schlender
PK-Sim example project for Caffeine
PK-Sim example project for Aciclovir
PK-Sim example project for Theophylline
PK-Sim example project for Paracetamol
PK-Sim® & MoBi® workshop on integrating PBPK with QSP
Whole-body PBPK model of theophylline as CYP1A2 DDI victim drug
Exemplary Protein PBPK Models
Modeling of published clinical Rifampicin-Theophylline-DDI studies for model evaluation
Modeling of published clinical Fluvoxamine-Theophylline-DDI studies for model evaluation
Modeling of published clinical Itraconazole-Digoxin-DDI studies for model evaluation
Modeling of published clinical Rifampicin-Digoxin-DDI studies for model evaluation
Modeling of published clinical Clarithromycin-Digoxin-DDI studies for model evaluation
Whole-body PBPK model of repaglinide as CYP2C8, CYP3A4, OATP1B1 and OATP1B3 DDI victim drug
Whole-body PBPK model of gemfibrozil as CYP2C8 and OATP1B1 DDI perpetrator drug
Whole-body PBPK model of pioglitazone as CYP2C8 DDI victim drug
Modeling of published clinical gemfibrozil-repaglinide-DDI studies for model evaluation
Modeling of published clinical gemfibrozil-pioglitazone-DDI studies for model evaluation
Modeling of published clinical itraconazole-repaglinide-DDI studies for model evaluation
Modeling of published clinical itraconazole-pioglitazone-DDI studies for model evaluation
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